Supernatural.
4X01 - "Lazarus rising"
Dean and Bobby are knocking on a door of hotel's room hoping to meet Sam. The door is opening and a brunette, surprised girl with amazing eyes appears. Her brief interaction with Dean and Bobby makes me laugh:
"So... where is it?"
"Where's what?"
"The pizza... that takes two guys to deliver?.."
And then -
"So are te two like... together?"
"What?No, no, he's my brother."
"O-oh, got it... I-I guess. Look, I should probably go..."

Unfortunately, I had no clue who this actress was.. But then I re-watched the beginning of the episode and this beautiful name Genevieve...