Angelina Jolie as Joan

Dennis Quaid as Hugh

Ellen Burstyn as Mildred

ghiandaia, jay Mohr as Mark

Ryan Phillippe as Keenan

Gena Rowlands as Hannah

Sean Connery as Paul

Gillain Anderson as Meredith

Anthony Edwards as Roger

Jon Stewart as Trent

Patricia Clarkson as Allison

April Grace as Valery

Alec Mapa as Lana

Christian Mills as Phillip

Kellie Waymire as Jane

Michael Emerson as Bosco

Tim Halligan as Cook mostra Director

John Patrick White as Pete

Amanda Peet as Amber

Michael B. Silver as Max

Chris Conner as Harry

Christopher Castile as Balley, Joan's bald overweight stepbrother

Alexa Chung as Mary, Keenan's red-haired sister

Torrey DeVitto as Lillith, Keenan's purple-haired sister

Marci Miller as Faith, Keenan's pink-haired sister

and più cast