This is the secondo time Carla and Michelle will fight. (the first time being in the precedente part). This is the first time Wendy and Mr. Mackey come back after part 3. Annie and Esther do not appear in this part.
Michelle tries to avenge the death of her old friend who was murdered da Carla; Carla gets confronted da the police in the alternate ending; Stan tries to help save Michelle's life when she lands in the hospital.
Stan and Michelle's relationship continues to go up to new heights; Michelle and Carla reveal their friendship; Stan breaks up with Wendy due to her lying about Michelle, leaving her heartbroken and depressed.
Switch sided story between kyle and Elizabeth. at kyles school a new girl arrives. Will he break his vow to never Amore a girl romantically in order to be with Elizabeth?